
Restylane® Refyne
in Naples, Ft. Myers & Marco
Subtle lines around the mouth and nose can make your expression look tired or tense—even when you feel your best. Restylane Refyne offers a refined, natural-looking way to soften these lines while still allowing your face to move naturally. Patients from Naples, Ft. Myers, and Marco trust this advanced dermal filler for results that look smooth, balanced, and authentically you.

What Is Restylane Refyne?
Restylane Refyne is a hyaluronic acid-based dermal filler specifically designed to soften moderate smile lines and facial folds. What sets it apart is its unique flexibility—it integrates seamlessly with your natural facial movements, allowing you to smile, talk, and laugh without stiffness.
Using advanced cross-linking technology, Restylane Refyne supports natural expression while improving skin smoothness and restoring youthful contour. The result is refined correction without an overfilled look.
Benefits of Restylane Refyne
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Softens moderate laugh lines and facial folds
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Preserves natural facial movement and expression
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Creates smooth, subtle enhancement
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Helps restore youthful contour and balance
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Immediate visible improvement with continued refinement
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Made with hyaluronic acid for smooth, hydrated-looking skin
Preparing for Treatment
Proper preparation helps promote the best possible outcome. Before your appointment, you may be advised to:
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Avoid blood-thinning medications or supplements when appropriate
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Limit alcohol consumption for 24 hours prior to treatment
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Arrive with clean skin and no active irritation in the treatment area
Your consultation will include a full assessment of your facial anatomy, skin quality, and aesthetic goals to ensure your treatment plan is tailored specifically to you.
Treatment with Restylane Refyne
Restylane Refyne treatment is performed in-office and typically takes less than an hour. The filler is injected with precise technique into targeted areas to soften lines while maintaining natural movement. The formulation includes lidocaine for improved comfort during treatment.
Throughout the process, careful attention is given to symmetry, balance, and subtle enhancement. Your provider adjusts the approach in real time to complement your facial structure and desired outcome.
Recovery and Aftercare
Most patients return to daily activities shortly after treatment. You may experience:
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Mild swelling
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Temporary redness
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Light bruising at injection sites
These effects typically resolve within a few days. You’ll be guided on simple aftercare steps, such as limiting intense exercise, heat exposure, and pressure on the treated areas for a short time to help your results settle beautifully.

Restylane Refyne Results
Results from Restylane Refyne are visible immediately and continue to refine as any initial swelling subsides. Treated areas appear smoother, softer, and more refreshed—without sacrificing natural facial movement.
Results are long-lasting, with many patients enjoying their outcome for up to a year or longer depending on individual metabolism, treatment area, and lifestyle factors.
Frequently Asked Questions About Restylane Refyne
How long does Restylane Refyne last?
Many patients enjoy results for approximately 9–12 months, sometimes longer.
Is Restylane Refyne safe?
Restylane Refyne is FDA-approved and has a well-established safety profile when administered by trained medical professionals.
Will I look overfilled?
Restylane Refyne is specifically designed to preserve natural expression while softening lines, helping prevent an overfilled appearance.
Is there downtime?
Most patients return to normal activities immediately, with minimal temporary swelling or redness.
Can Restylane Refyne be combined with other treatments?
Yes. Restylane Refyne is often paired with other aesthetic treatments such as injectable fillers for added volume, BOTOX® to soften dynamic wrinkles, microneedling to improve skin texture, and HydraFacial® treatments for enhanced skin hydration and glow as part of a comprehensive facial rejuvenation plan.
Contact Us
If you’re considering Restylane Refyne in Naples, Ft. Myers, or Marco, our team is here to help you explore your options and create a personalized aesthetic plan. Contact Yag-Howard Cosmetic Dermatology today to schedule your consultation and take the next step toward smoother, naturally refreshed skin.

¹ Yag-Howard C, DeNigris J. Novel Filler Technique: Hyaluronic acid and Calcium hydroxylapetite mixture resulting in favorable esthetic and longevity outcomes. Int J Womens Dermatol. 2021 Sep 27;7(5 Pt B):817-819. doi: 10.1016/j.ijwd.2021.09.008. PMID: 35028387; PMCID: PMC8714586. Available: https://pmc.ncbi.nlm.nih.gov/articles/PMC8714586/. Accessed August 8, 2025.
² Aesthetic Surgery Journal. The Role of Calcium Hydroxylapatite (Radiesse) as a Regenerative Aesthetic Treatment: A Narrative Review. https://pmc.ncbi.nlm.nih.gov/articles/PMC11025388/. Accessed May 8, 2025.
³ Aesthetic Surgery Journal. Calcium Hydroxyapatite (CaHA) Indication for Hand Rejuvenation. https://academic.oup.com/asj/article-abstract/38/suppl_1/S24/4961047. Accessed May 8, 2025.






